LEILA AZIMI¹, SOMAYEH SOLEYMANZADEH-MOGHADAM², LALEH AMANI ³, FARANAK ALINEJAD⁴, AIDA RASTEGAR LARI ⁵, ABDOLAZIZ RASTEGAR LARI⁶, FERYAL POURMOMEN BOLURCHI<sup>7

1</sup>Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, ²Department of Biology, University of Qom, Qom, Iran, ³Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, ⁴Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, ⁵Soins Infirmiers - CEGEP Limoilou, 1300 8e Av, Québec, QC G1J 5L5 Canada, ⁶Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, ⁷Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Aim: The aim of this study was to determine relationship between antibiotics prescribed and the results of antibiotic susceptibility testing in microbial laboratory in teaching burn hospital in Tehran, Iran.
Introduction: Burns and subsequent consequences are a global problem. Burn wound infection is one of the most common causes of death in burn injuries. Further, burn patients are at high risk for nosocomial infection. Thus, infection control in burn patients especially in the first 5 days after hospitalization is important. Infection control during this time period can prevent morbidity and mortality in these patients. Appropriate and accurate antibiotic prescription can be considered an important factor in increasing the awareness of patients about proper antibiotic use.
Methods: In this cross sectional study, we consider Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus as most important cause of nosocomial infection especially in burn patients. 525 strains of Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus were isolated from 335 hospitalized burn patients. Identification of the strains was performed by biochemistry and microbiological tests. Antibiotic susceptibility tests were performed according to CLSI guide line for each bacteria genus. The records were audited to find the antibiotic used.
Results: The results indicated that P. aeruginosa is the most prevalent Gram negative bacteria. The results of this study showed some antibiotics prescribed like, imipenem, amikacin, ciprofoloxacin and cefepime regardless of the antibiotics susceptibility responds in the lab.
Conclusion: Infection control is very important in burn care units, because burn wound infection is one of the main causes of morbidity and mortality among burn patients. Thus, the appropriate prescription of antibiotics can be helpful, but unreasonable prescription can have detrimental consequences, including greater expenses to patients and community alike.